It is used where inhibition of gastric acid secretion may be beneficial, as in peptic ulcer disease, including stress ulceration, gastro-eosophageal reflux disease, selected cases of persistent dispepsia, pathological hypersecretory states such as the Zollinger-Ellison syndrome and patients at risk of acid aspiration during general anaesthesia or child birth. It is also be used to reduce malabsorption and fluid loss in patient with the short bowel syndrome and to reduce the degradation of enzyme supplements given to patients with pancreatic insufficiency.
DRUG OF CHOICE FOR:
• Peptic Ulcer Dise
• Gastroesophageal reflux disease
• Patient With Infection
• Acid aspiration
The usual initial antihypertensive oral dose of amlodipine is 5 mg once daily with maximum dose of 10 mg once daily. Small, fragile or elderly individuals or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding Amlodipine to other antihypertensive therapy.
Dosage should be adjusted according to each patient's need. The recommended dose for chronic stable vasospastic angina is 5-10 mg with the lower dose suggested in the elderly and patients with hepatic insufficiency. Most patients will require 10 mg of for adequate effect.